Accurate Traceability of Stable C, H, O, N Isotope Ratios and Multi-Element Analysis Combined with Chemometrics for Chrysanthemi Flos ‘Hangbaiju’ from Different Origins

Chrysanthemi Flos ‘Hangbaiju’ (HBJ) is a common Chinese medicinal material with the same origin as and edible cognate plant in China, whose quality seriously affected by place of origin. In this study, four stable isotope ratios (δ15N, δ2H, δ13C, δ18O) 44 elements were detected analyzed 191 HBJ flower samples from six locations China to trace HBJ. An ANOVA analysis δ15N, δ18O values, well milti-elements, showed that there significant differences among places Partial least squares discriminant (PLSDA) one-class partial (OPLS-DA) models established these locations. The results classification effect PLSDA model poor; however, OPLS-DA can distinguish between products national geographic (Tongxiang City, Zhejiang Province, China) other origins, which Ni, Mo, Cu, Ce (VIP > 1) contribute most classification. Therefore, study provides new method for tracing origins HBJ, great significance protection labeling products.